Donatello (voice) 迈克·艾贝

Michelangelo (voice) 小肖恩·布朗

Leonardo (voice) 尼古拉斯·坎图

Raphael (voice) 布雷迪·诺恩

April O'Neil (voice) 阿尤·艾德维利

Cynthia Utrom (voice) 玛娅·鲁道夫

Rocksteady (voice) 约翰·塞纳

Bebop (voice) 塞斯·罗根

Leatherhead (voice) 萝丝·拜恩

Wingnut (voice) Natasia Demetriou

Baxter Stockman (voice) 吉安卡罗·埃斯波西托

Splinter (voice) 成龙

Superfly (voice) 艾斯·库珀

Mondo Gecko (voice) 保罗·路德

Ray Fillet (voice) 波兹·马龙

Genghis Frog (voice) 汉尼拔·伯雷斯

Times Square Guy (voice) 吉米·唐纳森

Spider (voice) Derek Wilson

Curious Goon (voice) Lukas Williams

Bad Bernie (voice) 迈克尔·巴达卢科

Bald Bronson (voice) Dempsey Pappion

Cab Driver (voice) 约翰·卡波迪斯

TV Anchor (voice) Andia Winslow

News Anchor (voice) Raechel Wong

Normal Nate (voice) David Faustino

Toupee Tom / Police Officer (voice) Danny Mastrogiorgio

Responding Police Officer / Military Advisor (voice) Noel Gibson

Short Sharon (voice) Myra Owyang

Good Human (voice) 凯文·伊斯特曼

Bossy Goon / Scumbug (voice) 亚历克斯·赫希

Paycheck Goon / Chop Shop Boss / Ratatouille Guard (voice) 迈克尔·里安达

Man Who Thought a Giant Rat was a Big Cat but was a Rat (voice) Bobby Wagner

Gecko Goon (voice) Greg Levitan

Helpful Construction Worker (voice) Illya Quinteros

Sign My Baby Mom (voice) Natalie Canizares

Apologetic Goon (voice) Kyler Spears

Man Who Loves Being Young and Free to Go Places (voice) 杰夫·罗韦

Ferris Bueller (archive footage) (uncredited) 马修·布罗德里克