James 'Jimmy' Isaac Neutron (voice) 黛比·德里贝里

Judy Neutron / VOX (voice) 梅根·卡瓦纳

Hugh Neutron / Pilot / Arena Guard (voice) Mark DeCarlo

Sheen Estevez (voice) Jeffrey Garcia

King Goobot V (voice) 帕特里克·斯图尔特

Ooblar (voice) 马丁·肖特

Goddard / Poultra (voice) 弗兰克·维尔克

Carl Wheezer / Mr. and Mrs. Wheezer / Kid in Classroom (voice) 罗布·保罗森

Cindy Vortex (voice) 卡罗琳·劳伦斯

Libby Folfax (voice) Crystal Scales

Nick Dean / Britney / PJ (voice) Candi Milo

Yokian Guard / Gus (voice) David L. Lander

Mr. Estevez (voice) 卡洛斯·阿拉斯拉基

Ultra Lord / Mission Control / General Bob (voice) 吉姆·卡明斯

Bobby / Kid / Control Yokian (voice) Keith Alcorn

Zachary / Reporter / Angie / Libby's Mom (voice) 金伯莉·布鲁克斯

Ms. Winfred Fowl (voice) 安德里亚·马丁

Bobby's Twin Brother (voice) / Butch (voice) / Jailbreak Cop (voice) / Old Man Johnson (voice) / Robobarber (voice) / Flurp Announcer (voice) / Yokian Officer (voice) / Anchor Boy (voice) / Guard (voice) 比利·维斯特

Yokian Newscaster #2 (voice) Mary Hart

Yokian Newscaster #1 (voice) Bob Goen

Norad Officer (voice) 迪·布拉雷·贝克尔

Hostess (voice) 拉瑞尼·纽曼

Octapuke Kid / Guard / Bennie (voice) John A. Davis

Guard (voice) Paul Greenberg

Yokian Incubator Operator (voice) Mark Menza

Little Girl / Camera Person (voice) Jeannie Elias

Chris (voice) 迈克·萩原舞

Digital Voice (voice) Richard Allen

Screamer (voice) Brian Capshaw

Screamer (voice) Cheryl Ray

Hyperactive Kid / Arena Yokian (voice) Matthew Russell